Search results for "Nitrogen Isotope"

showing 10 items of 59 documents

Heavy enzymes and the rational redesign of protein catalysts

2019

Abstract An unsolved mystery in biology concerns the link between enzyme catalysis and protein motions. Comparison between isotopically labelled “heavy” dihydrofolate reductases and their natural‐abundance counterparts has suggested that the coupling of protein motions to the chemistry of the catalysed reaction is minimised in the case of hydride transfer. In alcohol dehydrogenases, unnatural, bulky substrates that induce additional electrostatic rearrangements of the active site enhance coupled motions. This finding could provide a new route to engineering enzymes with altered substrate specificity, because amino acid residues responsible for dynamic coupling with a given substrate present…

010402 general chemistryProtein Engineering01 natural sciencesBiochemistryCatalysisEnzyme catalysisisotope effectsCatalytic DomainDihydrofolate reductaseMolecular BiologyAlcohol dehydrogenasechemistry.chemical_classificationalcohol dehydrogenasesCarbon Isotopesdihydrofolate reductasesbiologyBacteriaNitrogen Isotopes010405 organic chemistryConceptOrganic ChemistryAlcohol DehydrogenaseActive siteSubstrate (chemistry)Protein engineeringDeuteriumCombinatorial chemistrymolecular dynamics0104 chemical sciencesKineticsTetrahydrofolate Dehydrogenaseenzyme engineeringEnzymechemistrybiology.proteinBiocatalysisMolecular MedicineConcepts
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Interpretation of the nitrogen isotopic composition of Precambrian sedimentary rocks: Assumptions and perspectives

2016

International audience; Nitrogen isotope compositions in sedimentary rocks (d(15)N(sed)) are routinely used for reconstructing Cenozoic N-biogeochemical cycling and are also being increasingly applied to understanding the evolution of ancient environments. Here we review the existing knowledge and rationale behind the use of d(15)N(sed) as a proxy for the Precambrian N-biogeochemical cycle with the aims of (i) identifying the major uncertainties that affect analyses and interpretation of nitrogen isotopes in ancient sedimentary rocks, (ii) developing a framework for interpreting the Precambrian d(15)N(sed) record, (iii) testing this framework against a database of Precambrian d(15)N(sed) va…

010504 meteorology & atmospheric sciencesEarth scienceNitrogen isotopesMetamorphismGeologyNitrogen biogeochemical cycle010502 geochemistry & geophysicsEarly Earth01 natural sciencesIsotopes of nitrogenDiagenesisPaleontologyPrecambrianGeologic time scale13. Climate actionGeochemistry and Petrology[SDU]Sciences of the Universe [physics]Ocean oxygenationSedimentary rock14. Life underwaterPrecambrianCenozoicGeology[ SDU ] Sciences of the Universe [physics]0105 earth and related environmental sciences
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Isotopic Anthropology of Rural German Medieval Diet: Intra- and Inter-population Variability

2016

This study investigates the diet of an eleventh century CE parish community located in northwestern Germany. We assessed the isotopic compositions of human (n = 24) and faunal (n = 17) bone collagen (δ 13Ccol, δ 15Ncol) and human structural carbonate (δ 13Csc) using skeletal material recovered from the Dalheim cemetery. Traditional interpretation of the isotopic data indicates that Dalheim residents likely relied on a C3 plant-based diet and consumed some terrestrial animal products without evidence of marine resource input in the diet. Bivariate and multivariate models used as an additional means to assess diet indicate minor consumption of C4 plant foods in this community. The multivariat…

010506 paleontologyArcheologyArqueologia medievalPopulationFood consumption610 Medicine & healthBiological and Physical AnthropologyBiologyTerrestrial animalPlant foods01 natural sciences0601 history and archaeologySkeletal materialeducationmedieval Germany0105 earth and related environmental sciencesTrophic leveleducation.field_of_studyBone collagen060102 archaeologyEcologyisotopic modelling06 humanities and the artspaleodietbiology.organism_classificationPopulation variabilityArchaeologyAnthropology11294 Institute of Evolutionary Medicine3314 Anthropology3302 Archeologycarbon and nitrogen isotopes1204 Archeology (arts and humanities)Archaeological Anthropology
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Stable isotopes of fatty acids: current and future perspectives for advancing trophic ecology

2020

To understand consumer dietary requirements and resource use across ecosystems, researchers have employed a variety of methods, including bulk stable isotope and fatty acid composition analyses. Compound-specific stable isotope analysis (CSIA) of fatty acids combines both of these tools into an even more powerful method with the capacity to broaden our understanding of food web ecology and nutritional dynamics. Here, we provide an overview of the potential that CSIA studies hold and their constraints. We first review the use of fatty acid CSIA in ecology at the natural abundance level as well as enriched physiological tracers, and highlight the unique insights that CSIA of fatty acids can p…

0106 biological sciencesFood ChainEcology (disciplines)010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyTrophic levelIsotope analysis2. Zero hungerchemistry.chemical_classificationCarbon IsotopesEcologyNitrogen IsotopesStable isotope ratioEcology010604 marine biology & hydrobiologyFatty AcidsFatty acidArticlesDeuteriumFood webDietary Requirementschemistry13. Climate action[SDE]Environmental SciencesEnvironmental scienceResource use[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciences
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Diet and habitat use influence Hg and Cd transfer to fish and consequent biomagnification in a highly contaminated area: Augusta Bay (Mediterranean S…

2016

Abstract Total mercury (T-Hg) and cadmium (Cd) were measured in twenty species of fish to study their bioaccumulation patterns and trophodynamics in the Augusta Bay food web. Adult and juvenile fish were caught in 2012 in Priolo Bay, south of the Augusta harbour (Central Mediterranean Sea), which is known for the high trace element and polycyclic aromatic hydrocarbon contamination level. T-Hg concentration was found to significantly increase along δ15N and from pelagic to benthic sedentary fish, revealing a marked influence of trophic position and habitat use (sensu Harmelin 1987) on T-Hg accumulation within ichthyofauna. Cd showed the opposite pattern, in line with the higher trace element…

0106 biological sciencesFood ChainHealth Toxicology and MutagenesisBiomagnification010501 environmental sciencesBiologyToxicology01 natural sciencesZooplanktonMetals Contamination Fish Mercury Cadmium Stable isotopesMediterranean SeaAnimalsPolycyclic Aromatic HydrocarbonsEcosystem0105 earth and related environmental sciencesTrophic levelNitrogen IsotopesEcology010604 marine biology & hydrobiologyFishesPelagic zoneMercuryGeneral MedicineJuvenile fishPlanktonInvertebratesPollutionFood webDietTrace ElementsBaysBenthic zoneBayWater Pollutants ChemicalCadmiumEnvironmental MonitoringEnvironmental Pollution
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An Empirical Evaluation of the Utility of Convex Hull and Standard Ellipse Areas for Assessing Population Niche Widths from Stable Isotope Data

2013

Stable isotope analyses are increasingly employed to characterise population niche widths. The convex hull area (TA) in a δ¹³C–δ¹⁵N biplot has been used as a measure of isotopic niche width, but concerns exist over its dependence on sample size and associated difficulties in among-population comparisons. Recently a more robust method was proposed for estimating and comparing isotopic niche widths using standard ellipse areas (SEA), but this approach has yet to be tested with empirical stable isotope data. The two methods measure different kind of isotopic niche areas, but both are now widely used to characterise isotopic niche widths of populations. We used simulated data and an extensive e…

0106 biological sciencesPopulation Dynamicslcsh:MedicinePopulation Modeling01 natural sciencesTheoretical EcologyFood Web StructureStatisticsRange (statistics)lcsh:ScienceFreshwater EcologyCarbon Isotopeseducation.field_of_studyMultidisciplinaryEcologyδ13CEcologyStable isotope ratioStatisticsFishesBiogeochemistryisotopic nicheTrophic Interactionstrophic nicheCommunity Ecologyconvex hullResearch ArticlePopulationNichestable isotopesBiostatistics010603 evolutionary biologyNiche ConstructionNormal distributionBayesian ellipse areavakaat isotoopitAnimals14. Life underwaterStatistical MethodseducationBiologyEcological nicheNitrogen Isotopes010604 marine biology & hydrobiologylcsh:RComputational BiologySpecies InteractionsSample size determinationSample SizeravintolokeroEnvironmental scienceta1181lcsh:QPopulation EcologyEcosystem ModelingMathematicsPLOS ONE
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Seasonal variability of diet and trophic level of the gelatinous predator Pelagia noctiluca (Scyphozoa)

2018

13 pages, 5 figures, 2 tables, supplementary information https://doi.org/10.1038/s41598-018-30474-x

0106 biological sciencesSettore BIO/07 - EcologiaJellyfishFood ChainScyphozoaZoologylcsh:Medicine010603 evolutionary biology01 natural sciencesArticleZooplanktonPredationbiology.animalMediterranean SeaAnimals14. Life underwaterBites and StingsGonadslcsh:SciencePredatorTrophic levelCarbon IsotopesDetritusMultidisciplinarybiologyNitrogen Isotopes010604 marine biology & hydrobiologyFatty Acidslcsh:RScyphozoa15. Life on landPlanktonbiology.organism_classificationPelagia noctilucajellyfish stomach content stable isotope fatty acid food habit outbreak-forming speciesGastrointestinal Contents13. Climate actionPredatory Behaviorlcsh:QSeasonsBiomarkersScientific Reports
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Trophic ecology of a Late Pleistocene early modern human from tropical Southeast Asia inferred from zinc isotopes

2021

Tam Pà Ling, a cave site in northeastern Laos, has yielded the earliest skeletal evidence of Homo sapiens in mainland Southeast Asia. The reliance of Pleistocene humans in rainforest settings on plant or animal resources is still largely unstudied, mainly due to poor collagen preservation in fossils from tropical environments precluding stable nitrogen isotope analysis, the classical trophic level proxy. However, isotopic ratios of zinc (Zn) in bioapatite constitute a promising proxy to infer trophic and dietary information from fossil vertebrates, even under adverse tropical taphonomic conditions. Here, we analyzed the zinc isotope composition (66Zn/64Zn expressed as δ66Zn value) in the en…

0106 biological sciencesTaphonomyPleistocene[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropologyRainforestBiology010603 evolutionary biology01 natural sciencesStable carbon isotopes03 medical and health sciencesCaveAnimalsHumansAsia SoutheasternEcology Evolution Behavior and SystematicsHunter-gathererComputingMilieux_MISCELLANEOUS030304 developmental biologyTrophic levelCarbon Isotopes0303 health sciencesgeographyHomo sapiensgeography.geographical_feature_categoryNitrogen IsotopesFossilsEcologyTam Pà LingHominidaeDietEnamelHomo sapiensAnthropologyZinc IsotopesMammalHunter-gatherer[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyJournal of Human Evolution
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Seasonal and ontogenetic shifts in the diet of Arctic charr Salvelinus alpinus in a subarctic lake.

2010

Seasonal and ontogenetic shifts in the diet of Arctic charr Salvelinus alpinus were studied in a deep, ultra-oligotrophic lake in subarctic Finland from both stomach contents and the stable carbon (delta(13)C) and nitrogen (delta(15)N) isotope compositions of muscle and liver tissues. Both diet and isotope results indicated that the S. alpinus population relied mainly on littoral benthic energy sources. The strong littoral reliance appeared largely independent of season or fish size, although the data lacked small (total length, L(T),130 mm) and young (3 years) S. alpinus. Liver isotope values of intermediate-sized S. alpinus (200-350 mm), however, suggested exploitation of the increase in …

0106 biological sciencesTroutPopulationFresh WaterAquatic Science010603 evolutionary biology01 natural sciencesZooplanktonLittoral zoneAnimals14. Life underwatereducationEcology Evolution Behavior and SystematicsFinlandIsotope analysisSalvelinuseducation.field_of_studyCarbon IsotopesbiologyNitrogen IsotopesEcology010604 marine biology & hydrobiologyMusclesPelagic zonebiology.organism_classificationSubarctic climateGastrointestinal ContentsDietLiverSeasonsEnergy sourceJournal of fish biology
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Macrophytes shape trophic niche variation among generalist fishes.

2017

Generalist species commonly have a fundamental role in ecosystems as they can integrate spatially distinct habitats and food-web compartments, as well as control the composition, abundance and behavior of organisms at different trophic levels. Generalist populations typically consist of specialized individuals, but the potential for and hence degree of individual niche variation can be largely determined by habitat complexity. We compared individual niche variation within three generalist fishes between two comparable lakes in the Czech Republic differing in macrophyte cover, i.e. macrophyte-rich Milada and macrophyte-poor Most. We tested the hypothesis that large individual niche variation…

0106 biological sciencesecological nichesgeneralist specieshiili:Zoology and botany: 480 [VDP]Marine and Aquatic SciencesPredationlcsh:MedicinePlant ScienceGeneralist and specialist species01 natural sciencesekosysteemittyppiFood Web StructureMedicine and Health Sciencesahvensärkilcsh:ScienceTrophic levelCzech RepublickalatlajistokartoitusPerchMultidisciplinarybiologyEcologyEcologyFishesBiodiversityPlantsPlanktonsorvaTrophic Interactionsekologinen lokeroCommunity EcologyForage fishVertebratesRutilusResearch ArticleFreshwater EnvironmentsScardiniusFood ChainNicherudd010603 evolutionary biologyjärvetZooplanktonPlant-Animal InteractionsTšekkiAnimalsHerbivory:Zoologiske og botaniske fag: 480 [VDP]EcosystempopulaatiobiologiaNutritionEcological nichefishisotoopitNitrogen Isotopes010604 marine biology & hydrobiologyPlant EcologyEcology and Environmental Scienceslcsh:ROrganismsBiology and Life SciencesAquatic EnvironmentsBodies of Waterbiology.organism_classificationInvertebratesDietmacrophytesekosysteemit (ekologia)LakesFoodEarth Sciencesta1181lcsh:QvesikasvitravintoverkotPLoS ONE
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